Endocrine Abstracts

Introduction: Differentiated thyroid cancer has usually good prognosis and long-term survival. Distant metastasis ratio is 5–15%. Metastasis to cerebrum, breast, liver, kidney, muscle, and skin is relatively rare. The study of molecular mechanisms of PTC has demonstrated that BRAFV600E gene mutation is a significant event in the process of this disease.Case: 55-year-old-male patient who had multinodular goiter showed malignant cytology in fine-needl...

Introduction: Primary hyperparathyroidism (PHP), is generalized with calcium, phosphate, and bone metabolism disorder due to increased PTH secretion. It’s common in fifth and sixth decades. Nowadays, it’s widely detected by measurement of blood calcium and may be presented with minimal or no symptoms.Design: 102 patients with PHP admitted to Department of Endocrinology, between years of 2008–2013 were analyzed.Result...

Giant cell granuloma is a skeletal manifestation seen now rarely in hyperparathyroidism due to early recognition of the disease. Lesions usually occur in the areas of intense bone resorption. They can affect mandible, maxilla, clavicle, ribs and pelvic bones. Most of the patients who have primary hyperparathyroidism are asymptomatic and are discovered incidentally during laboratory examinations. Here, we represent a female patient who was referred to endocrinology clinics beca...